Antibiotic resistance and rational outpatient antibiotic treatment of upper respiratory tract infections in children

Authors

  • Oleksandr Dobrovanov A. Getlik Clinic for Children and Adolescents, Slovak Medical University and University Hospital in Bratislava, Slovakia
  • Oleksandr Nazarchuk National Pirogov Memorial Medical University, Vinnytsia
  • Katerina Dmitrieva National Pirogov Memorial Medical University, Vinnytsia

DOI:

https://doi.org/10.31636/prmd.v5i2.1

Keywords:

antibiotics, vaccination, post-antibiotic era, resistance, season of respiratory diseases, pain, discomfort

Abstract

On the eve of the season of respiratory infections, we would like to draw the attention of outpatient doctors to the fact that 80–90 percent of winter diseases affecting the nose, ears, throat and lungs are of viral origin. Improper and excessive consumption of antibiotics increases the risk of antibiotic resistance, and thus humanity enters the post-antibiotic era. The World Health Organization warns that the problems that antibiotic resistance could cause in the future can be compared to the spread of AIDS in the 1980s. The principles of rational use of antibiotics should always be based on the assumption that antibiotics are causal drugs, and their overuse very often leads to resistance, which negatively affects the entire population. Irrational antibiotic therapy can also lead to discomfort, worsening of acute and chronic pain. It is also important to know that in the post-antibiotic era, science has other options for fighting bacteria, such as vaccination, immunotherapy, and strengthening individual immunity. The correct attitude of doctors to the prevention of diseases and rational treatment with antibiotics can help reduce the resistance of bacterial strains, discomfort and pain.

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References

Im JH, Je YS, Baek J, Chung MH, Kwon HY, Lee JS. Nutritional status of patients with COVID-19. International Journal of Infectious Diseases [Internet]. 2020 Nov;100:390–3. Available from: https://doi.org/10.1016/j.ijid.2020.08.018

Jacobson MK, Jacobson EL. Vitamin B3 in Health and Disease: Toward the Second Century of Discovery. ADP-ribosylation and NAD+ Utilizing Enzymes [Internet]. 2018;3–8. Available from: https://doi.org/10.1007/978-1-4939-8588-3_1

Jovic TH, Ali SR, Ibrahim N, Jessop ZM, Tarassoli SP, Dobbs TD, et al. Could Vitamins Help in the Fight Against COVID-19? Nutrients [Internet]. 2020 Aug 23;12(9):2550. Available from: https://doi.org/10.3390/nu12092550

Lambert NJ, Corps Survivor. COVID-19 “long Hauler” Symptoms survey report [Internet]. Indiana University School of Medicine; 2020. 13 p. Available from: https://scholarworks.iupui.edu/handle/1805/25685

Krčméry V. Super-resistant bacteria: are we in the pre-antibiotic or post-antibiotic era? [Superrezistentné baktérie: sme v preantibiotickej alebo v postantibiotickej ére?]. Via pract [Internet]. 2011;8(1):6–8. Available from: https://www.solen.sk/storage/file/article/dcb83390d97bafd642a3549d96e40c06.pdf [In Slovak]

Kuchynková Z. Children's otolaryngology: the most common situation in ambulatory practice [Dětská otolaryngologie: nejčastější situace v ambulantní praxi]. Praha: Grada Publishing; 2015. p.144 [In Czech]

Králinský K, Štefkovičová M, Holečková K. Meningococcal infections — still an actual problem [Meningokokové infekcie – stále aktuálny problém]. Revue medicíny v praxi 2018;14(1):11–14. [In Slovak]

Líšková A. Rational antibiotic therapy of respiratory infections [Racionálna antibiotická terapia respiračných infekcií]. Primárny kontakt 2014;6(2):14–16. [In Slovak]

Torres A, Blasi F, Peetermans WE, Viegi G, Welte T. The aetiology and antibiotic management of community-acquired pneumonia in adults in Europe: a literature review. European Journal of Clinical Microbiology & Infectious Diseases [Internet]. 2014 Feb 15;33(7):1065–79. Available from: https://doi.org/10.1007/s10096-014-2067-1

Woodhead M, Blasi F, Ewig S, Garau J, Huchon G, Ieven M. Joint Taskforce of the European Respiratory Society and European Society for Clinical Microbiology and Infectious Diseases: Guidelines for the management of adult lower respiratory tract infections. Clin Microbiol Infect. 2011;17(6):1–24.

Linus Pauling Institute. Vitamin C [document on the Internet]. Oregon State University. [cited 2021 Aug 18]. Available from: https://lpi.oregonstate.edu/mic/vitamins/vitamin-C

Lopez-Leon S, Wegman-Ostrosky T, Perelman C, Sepulveda R, Rebolledo PA, Cuapio A, et al. More than 50 Long-term effects of COVID-19: a systematic review and meta-analysis. 2021 Jan 29; Available from: https://doi.org/10.1101/2021.01.27.21250617

Lu Y, Li X, Geng D, Mei N, Wu PY, Huang CC, et al. Cerebral Micro-Structural Changes in COVID-19 Patients — An MRI-based 3-month Follow-up Study. EClinicalMedicine [Internet]. 2020 Aug;25:100484. Available from: https://doi.org/10.1016/j.eclinm.2020.100484

Makarchikov AF. Vitamin B1: Metabolism and functions. Biochemistry (Moscow) Supplement Series B: Biomedical Chemistry [Internet]. 2009 May 16;3(2):116–28. Available from: https://doi.org/10.1134/s1990750809020024

Hedrick JA. Community-acquired upper respiratory tract infections and the role of third-generation oral cephalosporins. Expert Review of Anti-infective Therapy [Internet]. 2010 Jan;8(1):15–21. Available from: https://doi.org/10.1586/eri.09.115

Kučerová D. Macrolide ATB in the treatment of respiratory infections [Makrolidové ATB v liečbe respiračných infekcií]. Via pract [Inter-net]. 2010;7(2):66–69. Available from: https://www.solen.sk/casopisy/viapractica/makrolidove-atb-v-liecbe-respiracnych-infekcii [In Slovak]

Jarčuška P, Balogová L, Šuleková L, Vološinová D. Infections caused by chlamydia [Infekcie vyvolané chlamýdiami]. Via pract [Internet]. 2009;6(4):147–152. Available from: https://www.solen.sk/casopisy/via-practica/infekcie-vyvolane-chlamydiami [In Slovak]

Hotomi M, Yamanaka N, Samukawa T, Suzumot M, Sakai A, Shimada J, et al. Treatment and outcome of severe and non-severe acute otitis media. European Journal of Pediatrics [Internet]. 2005 Jan;164(1):3–8. Available from: https://doi.org/10.1007/s00431-004-1564-0

Huebner RE, Wasas AD, Hockman M, Klugman KP. Bacterial aetiology of non-resolving otitis media in South African children. The Journal of Laryngology & Otology [Internet]. 2003 Mar;117(3):169–72. Available from: https://doi.org/10.1258/002221503321192430

Stánéková A. Acute otitis media in children [Akútny zápal stredného ucha u detí]. Pediatr. Prax [Internet]. 2008;4:198–201. Available from: https://www.fmed.uniba.sk/uploads/media/Akutny_zapal_stredneho_ucha_u_deti_02.pdf [In Slovak]

Murphy TF, Parameswaran GI. Moraxella catarrhalis,a Human Respiratory Tract Pathogen. Clinical Infectious Diseases [Internet]. 2009 Jul;49(1):124–31. Available from: https://doi.org/10.1086/599375

European Committee on Antimicrobial Susceptibility Testing. MIC and zone diameter distributions and ECOFFs [document on the Internet]. European Society of Clinical Microbiology and Infectious Diseases. [cited 2021 Aug 18]. Available from: http://www.eucast.org/mic_distributions_and_ecoffs

Marchese A, Esposito S, Barbieri R, Bassetti M, Debbia E. Does the adoption of EUCAST susceptibility breakpoints affect the selection of antimicrobials to treat acute community-acquired respiratory tract infections? BMC Infectious Diseases [Internet]. 2012 Aug 6;12(1):181. Available from: https://doi.org/10.1186/1471-2334-12-181

Blahová J, Kraliková K, Krčméry V, Krčméry V, Babálová M, Menkyna R, et al. Monitoring of antibiotic resistance in Slovakia – Dynamics of resistance of microbes isolated from bacteraemia during 2002 –2003 [Monitorovanie rezistencie na antibiotiká v Slovenskej republike — dynamika rezistencie mikróbov izolovaných z bakteriémií v rokoch 2002–2003]. Lek Obzor. 2004;53(10): 372–376. [In Slovak]

Havers FP, Hicks LA, Chung JR, Gaglani M, Murthy K, Zimmerman RK, et al. Outpatient Antibiotic Prescribing for Acute Respiratory Infections During Influenza Seasons. JAMA Network Open [Internet]. 2018 Jun 8;1(2):e180243. Available from: https://doi.org/10.1001/jamanetworkopen.2018.0243

Makarov MV, Trammell SAJ, Migaud ME. The chemistry of the vitamin B3 metabolome. Biochemical Society Transactions [Internet]. 2018 Dec 17;47(1):131–47. Available from: https://doi.org/10.1042/bst20180420

Malik GR, Wolfe AR, Soriano R, Rydberg L, Wolfe LF, Deshmukh S, et al. Injury-prone: peripheral nerve injuries associated with prone positioning for COVID-19-related acute respiratory distress syndrome. British Journal of Anaesthesia [Internet]. 2020 Dec;125(6):e478–80. Available from: https://doi.org/10.1016/j.bja.2020.08.045

Moriguchi T, Harii N, Goto J, Harada D, Sugawara H, Takamino J, et al. A first case of meningitis/encephalitis associated with SARS-Coronavirus-2. International Journal of Infectious Diseases [Internet]. 2020 May;94:55–8. Available from: https://doi.org/10.1016/j.ijid.2020.03.062

Mucha SR, Dugar S, McCrae K, Joseph D, Bartholomew J, Sacha GL, et al. Coagulopathy in COVID-19: Manifestations and management. Cleveland Clinic Journal of Medicine [Internet]. 2020 May 14;87(8):461–8. Available from: https://doi.org/10.3949/ccjm.87a.ccc024

Dobrovanov O, Furková K, Vidiščák M, Húšťavová L. Multisystem inflammatory syndrome in children associated with COVID-19/SARS-CoV-2 mimicking Kawasaki disease (Kawa-COVID-19) [Multisys-témový zápalový syndróm u detí spojený s COVID-19/SARS-CoV-2, napodobňujúci Kawasakiho chorobu (Kawa-COVID-19)]. Pediatria (Bratisl.) [Internet]. 2020;15(5):300–303. Available from: https://www.amedi.sk/?amediController=magazine&amediMethod=content&amediId=9118 [In Slovak]

Dobrovanov O, Králinský K. Complications of COVID-19 in Children: PIMS-TS/MIS-C. Lek. Obzor [Internet]. 2022, 71(3): 100–153. Available from: https://www.researchgate.net/publication/360313081_ Complications_of_COVID-19_in_Children_PIMS-TSMIS-C

Dmytriiev D, Dobrovanov O. Post-COVID-19 pain syndrome. Anaesth. Pain & Intensive Care. 2021;25(4): 505–512.

Dmytriiev D, Dobrovanov O, Kralinsky K, Dmytriiev K, Melnychenko M. A case report of successful experience of using adaptive support ventilation in the pediatric patient with viral interstitial pneumonia COVID-19 positive. Lek. Obzor. 2021;70(3):119–123.

Kralinsky K, Pisarchikova M, Dobrovanov AE, Babela R. Protocol for the diagnosis, management and treatment of pediatric patients with COVID-19 according to the recommendations of the Slovakian Pediatric Society. Rossiyskiy Vestnik Perinatologii i Pediatrii (Russian Bulletin of Perinatology and Pediatrics) [Internet]. 2020 Nov 22;65(5):93–9. Available from: https://doi.org/10.21508/1027-4065-2020-65-5-93-99

Kovácsová E, Prochotský A, Dobrovanov A, Bodíková S, Andrisová J. Hypercoagulable state in COVID-19 infection, pathophysiology, treatment and its complications [Hyperkoagulačný stav pri infekcii COVID-19, patofyziológia, liečba a jej komplikácie]. Slov. chir [Internet]. 2022;19(1):20–23. Available from: https://www.solen.sk/casopisy/slovenska-chirurgia/hyperkoagulacny-stav-pri-infekcii-covid-19-patofyziologia-liecba-a-jej-komplikacie [In Slovak]

Ružický E, Mašán J, Šramka M. Artifi cial Intelligence to Rehabilita-tion for Post-COVID syndrome. Int J Health New Tech Soc Work [Internet]. 2021; 16(4): 149–158. Available from: https://www.ceeol.com/search/article-detail?id=1008988

Mašán J, Dobrovanov O, Čanecký A. Th e eff ect of cryotherapy on pain during local and total application. Pain medicine [Internet]. 2021 Apr 24;6(1):43–9. Available from: https://doi.org/10.31636/pmjua.v6i1.6

Dobrovanov O. Post-covid syndrome [Postkovidový syndróm]. Lekárnické listy. 2022;24(6):30-32. [In Slovak]

Dobrovanov O, Furkova K. Pandémia COVID-19: aktuality. Bratislava: Herba; 2022. р. 64. [In Slovak]

Semenkovych Y, Dmytriiev D, Dobrovanov O, Vidiščák M, Šupinová

M. Acute and chronic pain in children. A modern view of the issue. Lek. Obzor, Bratislava: Herba, 2022, 71 (9): 338–342.

Národné centrum zdravotníckych informácií (NCZI). [cited 2021 Aug 18]. Available from: http://www.nczisk.sk

Buc M. Autoimunita a autoimunitnmé choroby. Veda: SAV; 2005. p. 135–139.

Tenora J, Leblová Z, Prokeš Z. Transplantace stolice u dítěte. In: XX-VIII. Getlíkov deň. Novinky v pediatrii. Abstrakt Book. Bratislava: Pediatria; 2018;13(N1): P. 12.

Published

2023-01-29

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1.
Antibiotic resistance and rational outpatient antibiotic treatment of upper respiratory tract infections in children. prmd [Internet]. 2023 Jan. 29 [cited 2024 Mar. 29];5(2):4-12. Available from: https://perioperative.org.ua/index.php/prtmdc/article/view/105

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